Antimicrobial stewardship is an activity that includes appropriate selection, dosing, route, and duration of antimicrobial therapy.
The mission of Health PEI’s Antimicrobial Stewardship (AMS) program is to promote the optimal use of antimicrobials on PEI by providing accessible, up-to-date, evidence-informed guidance for treating common infections and advocating for responsible antimicrobial practices to protect the health of future generations.
All Health PEI guidelines and tools are also available on Firstline app.
Please download by visiting: https://firstline.org/health-pei/
PEI Antimicrobial Treatment Guidelines (Adults):
Respiratory:
- Adult Chemical Pneumonitis and Aspiration Pneumonia (2025) [PDF]
- Community Acquired Pneumonia (2025) [PDF]
- Hospital Acquired Pneumonia (2025) [PDF]
- Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) (2025) [PDF]
Other:
- Febrile Neutropenia (2025) [PDF]
- Clostridioides (Clostridium) difficile Infection (2023) [PDF]
- Diabetic Foot Infections (2023) [PDF]
- Gram Positive Cocci in Clusters Bacteremia (2016) [PDF]
- Lyme Disease Algorithm (2023) [PDF]
- Sepsis Syndromes
- Skin and Soft Tissue Infections (2023) [PDF]
- Urinary Tract Infection (2018) [PDF]
Useful Tools:
- Antibiogram 2025 PDF
- IV to PO Antimicrobial Step-down Guidelines (2020) [PDF]
- Virus Plan (October 2017) [PDF]
- Duration of Therapy Guideline - Antimicrobials [PDF]
- Clostridium difficile Risk with Specific Anti-infectives or Anti-infective Classes [PDF]
Beta-Lactam Allergy Management:
- Beta-Lactam Cross Allergy Matrix (2017) [PDF]
- Penicillin Allergy Management Algorithm (2017) [PDF]
- Management of Penicillin and Beta-Lactam Allergy Guidelines (2017) [PDF]
Please see the “Memos” section below for: Management of Beta-Lactam Allergies Bulletin, Beta-Lactam Allergy Management and PEI Provincial Guidelines Presentation, and Beta-lactam Cross Reaction Allergy Alert Modifications memo.
Malaria:
- Canadian Malaria Network Standard Operating Procedure (Version 1) [PDF]
- CMN Complete Malaria Package [PDF]
Stewardship Spotlight:
- IV Amoxicillin-Clavulanate Updates (For Adults) (January 2025) [PDF]
- Metronidazole BID vs TID (November 2024) [PDF]
- Did you Know - Firstline App (June 2025)
Antimicrobial Stewardship Program Metrics:
Semi-Annual Reports:
- Volume 1 (July 2025) [PDF]
Surveys:
- Firstline User Experience Survey Results (June 2025) [PDF]
Memos:
- 2025-05-12 | Emperic Antimicrobial Management of AECOPD[PDF]
- 2025-03-10 | Febrile Neutropenia in High Risk Adults[PDF]
- 2025-02-20 | Empiric Antimicrobial Management of Pneumonia [PDF]
- 2024-02-26 Health PEI Antibiogram 2024: Highlight of Practice Points PDF
- 2023-08-02 | IV Amoxicillin/Clavulanate Now Available in Hospital PDF
- 2020-01-16 | Beta-lactam Cross Reaction Allergy Alert Modifications [PDF]
- 2019-07-30 | Updated Clostridioides (Clostridium) difficile Infection Treatment Guidelines in Adults [PDF]
- 2017-11-14 | Management of Beta-Lactam Allergies Bulletin (November 2017) [PDF]
- 2017-11-14 | Beta-Lactam Allergy Management and PEI Provincial Guidelines Presentation (November 2017) [PDF]
- 2014-09-15 | Linezolid and Daptomycin Formulary Restrictions [PDF]
For questions please contact Fiona Mitchell (Provincial Antimicrobial Stewardship Pharmacist; 902-894-2587; fcmitchell@ihis.org).